Endometriosis & Fertility: Diagnosis and Treatment Options

Struggling to Conceive? Endometriosis May Be the Missing Link.
Endometriosis is one of the most common and often overlooked causes of infertility. At Advanced Fertility Center of Texas, we specialize in identifying and treating endometriosis-related infertility using a personalized, science-driven approach.  Whether you have painful periods, unexplained fertility struggles, or a confirmed diagnosis, our team is here to help uncover the root cause and create a clear path forward.

What Is Endometriosis?

Endometriosis occurs when tissue similar to the uterine lining grows outside the uterus, often on the ovaries, fallopian tubes, or pelvic cavity. This tissue responds to hormonal changes, causing chronic inflammation, scarring, and pain, and it can significantly interfere with fertility. Many patients with endometriosis go undiagnosed for years, even after repeated failed attempts to conceive.

How Endometriosis Affects Fertility

Endometriosis may reduce your chances of getting pregnant in several ways:

  • Inflamed or blocked fallopian tubes
  • Ovarian cysts (endometriomas) that damage egg quality
  • Pelvic adhesions that distort reproductive anatomy
  • Inflammatory environment that prevents implantation
  • Hormonal disruption affecting ovulation and uterine receptivity


Even women with mild or “silent” endometriosis may have difficulty conceiving — especially if no other cause is found.

Common Symptoms (Even Without a Diagnosis)

Do any of these sound familiar? 

  • Painful periods or heavy bleeding 
  • Pelvic pain during sex or bowel movements 
  • Chronic bloating or digestive issues 
  • Difficulty getting pregnant despite regular cycles 
  • Prior history of ovarian cysts, fibroids, or “unexplained infertility” 


If so, it’s worth a closer evaluation for possible endometriosis. 

How We Diagnose Endometriosis at AFCT

We use a combination of non-invasive and advanced diagnostic tools:

  • Pelvic ultrasound & Doppler imaging
  • Saline sonohysterogram (SIS)
  • Hysteroscopy or laparoscopy (when indicated)
  • Fertility hormone & inflammation testing
  • Ovarian reserve and egg quality evaluation


We also evaluate how endometriosis may be impacting implantation, egg development, and IVF outcomes.

Fertility Treatment Options for Endometriosis at AFCT

At AFCT, we tailor your treatment based on your goals, age, symptoms, and severity of disease. We do not follow a one-size-fits-all protocol — instead, we offer:  

Minimally Invasive Treatment
  • Hormonal support to regulate cycles and reduce inflammation. 
  • Strategic use of GnRH agonists or other medications to suppress endometrial activity before IVF. 
  • Anti-inflammatory protocols and antioxidant therapy through Lisanne Wellness. 
Fertility-Focused Surgery
  • We offer access to expert laparoscopic surgeons when removal of endometriosis lesions or cysts is needed to improve IVF or IUI outcomes
  • Surgery is often considered for:
  • Endometriomas (ovarian cysts)
  • Tubal obstruction
  • Pelvic adhesions or frozen pelvis
  • Failed IVF due to suspected pelvic disease
IVF with Endometriosis-Specific Protocols
  • Freeze-All IVF cycles to bypass inflammation during fresh transfer
  • Tailored stimulation protocols to protect egg quality
  • Estrogen priming and thin lining support
  • Embryo biopsy with PGT-A when needed
  • We treat many patients who have failed IVF elsewhere due to unrecognized or undertreated endometriosis.
  • Shape

Minimally Invasive Treatment

  • Hormonal support to regulate cycles and reduce inflammation. 
  • Strategic use of GnRH agonists or other medications to suppress endometrial activity before IVF. 
  • Anti-inflammatory protocols and antioxidant therapy through Lisanne Wellness. 

Fertility-Focused Surgery

  • We offer access to expert laparoscopic surgeons when removal of endometriosis lesions or cysts is needed to improve IVF or IUI outcomes
  • Surgery is often considered for:
  • Endometriomas (ovarian cysts)
  • Tubal obstruction
  • Pelvic adhesions or frozen pelvis
  • Failed IVF due to suspected pelvic disease

IVF with Endometriosis-Specific Protocols

  • Freeze-All IVF cycles to bypass inflammation during fresh transfer
  • Tailored stimulation protocols to protect egg quality
  • Estrogen priming and thin lining support
  • Embryo biopsy with PGT-A when needed
  • We treat many patients who have failed IVF elsewhere due to unrecognized or undertreated endometriosis.
  • Shape

Integrative Fertility Support

In collaboration with Lisanne Wellness Center, we offer functional and lifestyle-based support to reduce inflammation, optimize the uterine environment, and improve implantation outcomes.  Programs may include: 
  • Anti-inflammatory nutrition 
  • Endometrial microbiome support 
  • Acupuncture and lymphatic drainage 
  • Targeted supplement protocols   

Integrative Fertility Support

In collaboration with Lisanne Wellness Center, we offer functional and lifestyle-based support to reduce inflammation, optimize the uterine environment, and improve implantation outcomes.  Programs may include: 
  • Anti-inflammatory nutrition 
  • Endometrial microbiome support 
  • Acupuncture and lymphatic drainage 
  • Targeted supplement protocols   

Who We Help

We specialize in supporting: 

  • Women with suspected but undiagnosed endometriosis 
  • Patients with confirmed endometriosis struggling to conceive 
  • Women with endometriomas, blocked tubes, or unexplained infertility 
  • Patients with prior failed IUI or IVF attempts  

Take the Next Step

If you’re struggling with infertility and think endometriosis may be a factor — or have already been diagnosed and are looking for real solutions — we are here to help.   

Schedule a Fertility Evaluation 
Explore IVF for Complex Cases 
Learn More About Fertility Wellness 
Understand the IVF Process 

Scientific Research

Luteinizing hormone–independent rise of progesterone as the physiological trigger of the ovulatory gonadotropins surge in the human

Fertility and Sterility
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Recipient outcomes in an oocyte donation programme: should very young donors be excluded?

RBMO Oocyte Donation Programme
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