UNDERSTANDING INFERTILITY CAUSES

What's Preventing Pregnancy? The Top Causes of Infertility and How We Help

Infertility can have many different causes sometimes involving the woman, the man, or both. At Advanced Fertility Center of Texas (AFCT), we specialize in identifying why pregnancy isn't happening and creating a treatment plan tailored to your unique situation. Below are the most common causes of infertility each with proven solutions at AFCT.

UNDERSTANDING FERTILITY

Common Fertility Conditions

PCOS

PCOS (Polycystic Ovary Syndrome)

PCOS is one of the most common causes of infertility and is linked to hormonal imbalances that prevent normal ovulation. Women with PCOS often have irregular or absent menstrual cycles, making it harder to predict fertile windows.

We treat PCOS-related infertility with ovulation induction medications, lifestyle support, and metabolic care to improve ovulation and egg quality.

Ovulation Disorders

Ovulation Disorders

Conditions like PCOS, thyroid dysfunction, or hormonal irregularities can prevent the release of a mature egg each month. Without ovulation, pregnancy is unlikely.

AFCT offers ovulation induction with Clomid, Letrozole, or injectables, combined with fertility-focused wellness care to restore healthy cycles.

Endometriosis

Endometriosis

Endometriosis is a condition where tissue similar to the uterine lining grows outside the uterus—on the ovaries, fallopian tubes, or pelvic organs. It can cause inflammation, pain, scar tissue, and fertility challenges by impacting egg quality, blocking tubes, or reducing uterine receptivity.

We create personalized treatment plans for endometriosis-related infertility, often combining IVF with specialized uterine cavity treatments to improve success.

Fibroids

Fibroids & Uterine Polyps

Fibroids and polyps are benign growths in or around the uterus. While not all fibroids affect fertility, those that distort the uterine cavity can interfere with implantation or increase miscarriage risk.

AFCT uses advanced imaging to evaluate fibroids and coordinates minimally invasive treatments when they impact your fertility.

Ovarian Reserve

Low Ovarian Reserve & Egg Quality

The number and quality of eggs decline with age, but some women experience diminished ovarian reserve earlier than expected due to genetics, prior surgery, or medical conditions.

We provide AMH testing, tailor IVF stimulation protocols, and offer ovarian rejuvenation to improve ovarian response.

POI

Premature Ovarian Insufficiency (POI)

Also called early menopause, POI happens when the ovaries stop functioning properly before age 40. Women may still ovulate occasionally but need specialized fertility care.

We offer individualized protocols, fertility preservation options, and donor egg IVF if needed.

Tubal Issues

Tubal Damage or Blockages

Blocked or damaged fallopian tubes—caused by past infections, surgery, or endometriosis—can prevent the egg and sperm from meeting naturally.

AFCT diagnoses tubal issues with HSG imaging and uses IVF to bypass the tubes entirely.

Uterine Lining

Thin or Non-Receptive Uterine Lining

A thin endometrium can prevent even the healthiest embryos from implanting. This may result from hormonal issues, scarring, or reduced blood flow.

We offer uterine cavity rejuvenation, hormonal support, and integrative wellness to optimize implantation receptivity.

Cervical Issues

Cervical Mucus Issues

In some cases, cervical mucus is too thick or hostile for sperm to travel through the cervix and reach the egg.

IUI or IVF can bypass cervical barriers and improve fertilization chances.

Genetic Factors

Genetic & Hormonal Factors

Certain genetic variations, like MTHFR mutations, or chromosomal abnormalities can lead to failed implantation, miscarriage, or inherited conditions.

AFCT offers Preimplantation Genetic Testing (PGT-A, PGT-M), advanced hormone testing, reproductive immunology, and methylated prenatal vitamins to optimize implantation success.

Microbiome

Microbiome Imbalances

An unhealthy vaginal or uterine microbiome can cause inflammation, reduce implantation rates, and increase miscarriage risk.

We provide microbiome testing and targeted probiotic therapy like Biomegil™ to restore a healthy reproductive environment.

OTHER FACTORS

Male Fertility & Combined Causes

Male Fertility

Male Factor Infertility

Male infertility can be caused by low sperm count, poor motility, abnormal shape, or even prior vasectomy. DNA fragmentation or environmental factors may also affect sperm quality.

Here at AFCT, we provide advanced semen analysis, sperm retrieval techniques (TESE), and ICSI (Intracytoplasmic Sperm Injection) to overcome male infertility challenges.

Unexplained Infertility

Unexplained Infertility

In about 20% of couples, all standard tests look normal, yet pregnancy doesn't happen.

We use advanced diagnostics, customized IVF protocols, and reproductive immunology to uncover hidden causes and improve outcomes.

Age-Related Fertility

Age-Related Fertility Decline

Female egg quality declines significantly after age 35, while male sperm quality can also decrease over time.

We offer fertility preservation (egg, sperm, embryo freezing) and advanced IVF options to overcome age-related fertility challenges.

Why Finding the Cause Matters

Identifying the root cause of infertility helps us create a personalized treatment plan—saving time, reducing stress, and improving your chances of success.

At AFCT, we combine

Advanced fertility testing & diagnostics
Customized treatment protocols
Integrative wellness & cutting-edge lab techniques

Ready for answers? Schedule your fertility consultation today.

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Scientific Research

Luteinizing hormone–independent rise of progesterone as the physiological trigger of the ovulatory gonadotropins surge in the human

Fertility and Sterility
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Recipient outcomes in an oocyte donation programme: should very young donors be excluded?

RBMO Oocyte Donation Programme
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